The Food and Drug Administration on Monday greenlighted updated Covid boosters from Pfizer and Moderna. The shots, which are formulated to target the XBB.1.5 subvariant, are expected to be available later this week, after the Centers for Disease Control and Prevention signs off.

Anyone age 5 and older can get an updated booster shot from either Pfizer-BioNTech or Moderna, regardless of whether they were previously vaccinated, the FDA said in a statement. People who have been vaccinated should wait at least two months before getting the updated booster.

The boosters come as Covid cases are rising in the U.S., driven by a slew of subvariants. Officials hope that the boosters can blunt a possible spike in winter illness.

For the first time since the vaccines became available, the federal government will not cover the cost of the shots.

Pfizer and Moderna have said they are pricing each vaccine dose at over $100.

Jennifer Kates, director of the Global Health & HIV Policy Program at the nonprofit KFF, said most people with private and public health insurance should continue to pay nothing out of pocket for the boosters — as long as they stick with an in-network provider.

People who don’t have insurance — an estimated 30 million in the U.S. — should be able to get a booster for free at community health centers. Additionally, the Biden administration is also rolling out a “bridge” program that will offer uninsured people access to free boosters at least through the end of 2024. Those who don’t know or don’t have access to these resources may have to pay out of pocket, she said.