Sure. Depends on your situation, if you need to be in a particular place, or whatever else.
For my own situation, I would need to go really rural. Homes being built 20-30 minutes more rural than where I am are priced higher than my current home. I could move further out and build, but the tradeoff is construction not being a ton cheaper, and extending commutes to 1.5 hours each direction. I take care of my elderly mother, so fast access to medical services is also important.
I’d actually love to be more rural myself, I’m just stuck in a situation where getting everyone what they need dictates a certain radius, barring picking everyone up and migrating elsewhere entirely.
The link seems obvious, honestly. If you get a vaccine, that’s .5ml adding to your body weight… you go get in a pool without factoring that in, next thing you know, you’re at the bottom running out of air. If he ate within half an hour of getting in… well, he was just courting death at that point.